July 31 2021
The progression of osteoarthritis has till now unfortunately not been found to have any permanent cure to either stop or limit the spread of the disease. In some patients going through the osteoarthritis pain though, it has been studied that supplementing with chondroitin and glucosamine can provide some relief to arrest the progression of the symptoms.
The basic property of chondroitin sulfate and glucosamine supplements put into use is that they can act of the underlying cause of osteoarthritis pain by playing an important role in the slowdown and preventing the degeneration of joint cartilage thereby providing relief from the incessant joint pain. Another reason for the preference of the use of the chondroitin and glucosamine supplements rather than the conventional line of osteoarthritis treatment is that they do not exhibit many side effects.
Functions of glucosamine and chondroitin sulfate
Chondroitin sulfate is mainly found in the animal cartilages of trachea or shark cartilage whereas glucosamine is derived from some animal tissues which include crab, lobster, shrimp. Both glucosamine and chondroitin sulfate are naturally present in the human body in the connective tissues especially as the coverings of the edges of the bones and around the joints. Chondroitin sulfate and glucosamine supplements are manufactured by Alvizia healthcare by the name of ‘joint complex’ which are to be supplemented orally. The impact of glucosamine and chondroitin sulfate on the cartilage degeneration procedure taking place in osteoarthritis is the following:
Chondroitin sulfate is a component of the protein structure which is responsible for providing elasticity to the cartilage and it is also involved in establishing an anti-inflammatory effect which in turn decreases the occurrence of pain and swelling in the joints which takes place as a result of rubbing together of the exposed bones in the joints:
Glucosamine lays down the pathway for cartilage formation and repair. By inhibiting breakdown and the construction of the various levels of cartilage, glucosamine sulfate invariably helps to protect cartilage in the joints. They also get more readily absorbed in the body thereby requiring lower dosage. The consumption of these supplements may ultimately reduce the need for undergoing total knee replacement surgery in those with chronic osteoarthritis.
It has also been found that people who take chondroitin and glucosamine along with lifestyle modifications also have a much lesser chance of developing cardiovascular disease.
Chondroitin and glucosamine intake regularly also shows to be an indicator of having a lower risk of developing diabetes. A combination of glucosamine sulfate, methylsulfonylmethane, white willow bark, ginger root, turmeric and hyaluronic acid in equal proportions for three weeks shows remarkable reduction in the symptoms of chronic knee pain as well as causes improvement in the knee movement.
Supplementing with chondroitin sulfate and glucosamine also decreases the chance of relapse in the case of multiple sclerosis. Regular intake of chondroitin and glucosamine also reduces the risk of getting a stroke. In the painful condition such as jaw pain, these supplements in association with non-steroidal anti-inflammatory drugs such as ibuprofen, show great benefits in the pain relief. Other conditions in which these supplements can be used are glaucoma where the eye disease can lead to loss of vision, interstitial cystitis which is defined as the painful bladder syndrome and weight loss.
It has been found that injection of chondroitin and sodium hyaluronate into the eye during cataract surgery has protective effects on the eye as it reduces the pressure within the eye and causes an overall improvement in eye health after cataract removal. Administration of these supplements through a catheter for four weeks shows markedly reduced urinary tract infections in women with a history of manifestation of UTIs.
These supplements when used in the form of eye drops decreases the occurrence of dry eyes. In combination with antacids, chondroitin sulfate and glucosamine supplements appear to reduce the intensity of acid reflux symptoms.
Injection of chondroitin sulfate into the bladder along with hyaluronic acid causes relief from the symptoms of bladder inflammation. In the bone and joint disease called Kashin - Beck syndrome, the application of chondroitin and glucosamine can reduce the joint pain and also slow down the narrowing of the joint space associated with this condition.
Intake of chondroitin sulfate orally has been found to decrease the risk of suffering from a heart attack. Taking chondroitin supplements for about three months leads to an improvement in the skin redness and irritation associated with psoriasis. But these supplements are not very beneficial in people who have the underlying condition of osteoarthritis. The introduction of chondroitin sulfate into the bladder by the means of a urinary catheter has shown to improve the quality of life in those suffering from urinary incontinence.
Glucosamine supplements have been known to suppress the changes that can initiate irritable bowel syndrome, reduce the immune response that may be associated with multiple sclerosis and improve the knee mobility which could be damaged as a result of sports-related injury.
Side effects of glucosamine and chondroitin supplements intake are usually mild and may include symptoms such as nausea, heartburn, diarrhoea, dizziness, constipation, drowsiness, allergic skin reactions and headaches. Intake of these supplements along with food can reduce the onset of these symptoms.
These supplements should be taken only in consultation with a healthcare physician specifically in those suffering from underlying conditions such as asthma, glaucoma, hypercholesterolemia, hypertension. Pregnant and breastfeeding women should avoid intake of these supplements as they are not yet considered to be safe in these conditions. These supplements should also be avoided in combination with blood-thinning drugs like warfarin which may cause severe bleeding.